Science
A blueprint for tumor-infiltrating B cells across human cancers | Science (Fr, 03 Mai 2024)B lymphocytes are essential mediators of humoral immunity and play multiple roles in human cancer. To decode the functions of tumor-infiltrating B cells, we generated a B cell blueprint encompassing single-cell transcriptome, B cell–receptor repertoire, ...
>> mehr lesen
A single cell atlas of sexual development in Plasmodium falciparum | Science (Fri, 03 May 2024)
The developmental decision made by malaria parasites to become sexual underlies all malaria transmission. Here, we describe a rich atlas of short- and long-read single-cell transcriptomes of over 37,000 Plasmodium falciparum cells across ...
>> mehr lesen
Induction of social contagion for diverse outcomes in structured experiments in isolated villages | Science (Fri, 03 May 2024)
Certain people occupy topological positions within social networks that enhance their effectiveness at inducing spillovers. We mapped face-to-face networks among 24,702 people in 176 isolated villages in Honduras and randomly assigned villages to ...
>> mehr lesen
CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication | Science (Fri, 03 May 2024)
Cell cycle events are coordinated by cyclin-dependent kinases (CDKs) to ensure robust cell division. CDK4/6 and CDK2 regulate the growth 1 (G1) to synthesis (S) phase transition of the cell cycle by responding to mitogen signaling, promoting E2F ...
>> mehr lesen
News at a glance: Infrared telescope debuts, GM rice stumbles, and maternal mortality drops (Thu, 02 May 2024)
The latest in science and policy
>> mehr lesen
A scientist is likely to win Mexico’s presidency. Not all researchers are rejoicing (Thu, 02 May 2024)
Claudia Sheinbaum Pardo would be first researcher to lead the country, but critics worry she’ll be as hostile to science as her predecessor
>> mehr lesen
Locally narrow droplet size distributions are ubiquitous in stratocumulus clouds | Science (Thu, 02 May 2024)
Marine stratocumulus clouds are the “global reflectors,” sharply contrasting with the underlying dark ocean surface and exerting a net cooling on Earth’s climate. The magnitude of this cooling remains uncertain in part owing to the averaged ...
>> mehr lesen
In Other Journals | Science (Thu, 02 May 2024)
Editors’ selections from the current scientific literature
>> mehr lesen
In Science Journals | Science (Thu, 02 May 2024)
Highlights from the Science family of journals
>> mehr lesen
Noncharismatic species also need protection | Science (Thu, 02 May 2024)
Global biodiversity decline is a pressing environmental challenge in the 21st century (1), and both international platforms, such as the United Nations Conference of the Parties (2), and regional development plans [e.g., (3)] focus on biodiversity conservation. However, because of the public appeal of charismatic species, research resources are predominantly invested in birds and mammals (4) and often exclude noncharismatic species, such as fish, insects, and plants. Contrary to perceptions, the ecological and economic consequences of noncharismatic species are often substantial. Researchers must study noncharismatic species to inform balanced biodiversity goals (5).
>> mehr lesen
Protect Pakistan’s otters | Science (Thu, 02 May 2024)
Pakistan is home to two otter species, the Eurasian otter (Lutra lutra) and the smooth-coated otter (Lutrogale perspicillata). Two decades ago, these species thrived in habitats across Pakistan, but now they are limited to isolated patches in their range (1), are classified as Near Threatened in Pakistan (2), and are listed in Appendix II of the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) (3). Pakistan must take steps to protect otters.
>> mehr lesen
Nextgen Voices: Preventing Bad Behavior | Science (Thu, 02 May 2024)
Add your voice to Science! Our new NextGen Voices survey is now open: What one change to scientifi c policy or culture would substantially decrease incidents of scientifi c misconduct or other unethical behavior?
>> mehr lesen
Groundwater flooding risks overlooked | Science (Thu, 02 May 2024)
HomeScienceVol. 384, No. 6695Groundwater flooding risks overlookedBack To Vol. 384, No. 6695 Full accessLetter Share on Groundwater flooding risks overlookedHamid M. Behzad and Yunpeng Nie [email protected]Authors Info & AffiliationsScience2 May 2024Vol 384, Issue 6695pp. 518-519DOI: 10.1126/science.ado6820 PREVIOUS ARTICLEPandemics and their accelerantsPreviousNEXT ARTICLENextgen Voices: Prevent…
>> mehr lesen
Pandemics and their accelerants | Science (Thu, 02 May 2024)
A well-researched account of the factors that drive pandemics misses an opportunity to indict broader social systems
>> mehr lesen
Darwin meets Dickinson | Science (Thu, 02 May 2024)
The biologist and the poet shared deep sensibilities about the natural world
>> mehr lesen
Daniel Kahneman (1934–2024) | Science (Thu, 02 May 2024)
Pioneer in the psychology of judgment and decision-making
>> mehr lesen
Zombie malaria parasites | Science (Thu, 02 May 2024)
Natural infections are distinct from those of laboratory—or zombie—strains
>> mehr lesen
A reverse brake for the cell cycle | Science (Thu, 02 May 2024)
Mitogenic signaling acts beyond S-phase entry to prevent whole-genome duplications
>> mehr lesen
B cell trajectories influence cancer outcomes | Science (Thu, 02 May 2024)
Two types of B cell in the tumor microenvironment modulate antitumor immunity
>> mehr lesen
Conductive hydrogels put electrons in charge | Science (Thu, 02 May 2024)
Semiconductor hydrogels enable active bioelectronics
>> mehr lesen
Unsettled science on longer-run effects of early education | Science (Thu, 02 May 2024)
More rigorous research is needed on how to design programs
>> mehr lesen
A fellow engineer and presidential rival | Science (Thu, 02 May 2024)
HomeScienceVol. 384, No. 6695A fellow engineer and presidential rivalBack To Vol. 384, No. 6695 Full accessFeature Share on A fellow engineer and presidential rivalRodrigo Pérez OrtegaAuthors Info & AffiliationsScience2 May 2024Vol 384, Issue 6695p. 504DOI: 10.1126/science.adq1748 PREVIOUS ARTICLEA scientist for presidentPreviousNEXT ARTICLEConductive hydrogels put electrons in chargeNext Conte…
>> mehr lesen
Scientists call new measures to control bird flu in cows ‘a drop in the bucket’ (Wed, 01 May 2024)
As restrictions take effect, new data show virus is pervasive in herds
>> mehr lesen
Steel industry emissions are a big contributor to climate change. Can it go green? (Wed, 01 May 2024)
Department of Energy funds research to take carbon out of iron and steel production
>> mehr lesen
Nobel-winning neuroscientist faces scrutiny for data discrepancies in more than a dozen papers (Wed, 01 May 2024)
Thomas Südhof says mistakes in co-authored publications are honest errors that don’t affect studies' conclusions
>> mehr lesen
Ancient crystals suggest early Earth had land and freshwater (Wed, 01 May 2024)
Hardy zircon minerals found in Australian rocks suggest conditions for life existed 4 billion years ago
>> mehr lesen
Major budget cuts to two high-profile NIH efforts leave researchers reeling (Wed, 01 May 2024)
Drop in 21st Century Cures Act funding will slow BRAIN and All of Us projects
>> mehr lesen
A pandemic agreement is within reach | Science (Tue, 30 Apr 2024)
At the end of May, 194 member states of the World Health Organization (WHO) will meet for the World Health Assembly. Negotiations underway now will determine whether they vote then to adopt a pandemic agreement. For the past 2 years, discussions have ...
>> mehr lesen
Climate modelers grapple with their own carbon emissions (Tue, 30 Apr 2024)
Next round of international climate simulations will seek to curb excess energy use for computation
>> mehr lesen
Human telomere length is chromosome end–specific and conserved across individuals | Science (Thu, 11 Apr 2024)
Short telomeres cause age-related disease, and long telomeres contribute to cancer; however, the mechanisms regulating telomere length are unclear. We developed a nanopore-based method, which we call Telomere Profiling, to determine telomere length at ...
>> mehr lesen